Pigmented progressive purpuric dermatosis
https://en.wikipedia.org/wiki/Pigmented_purpuric_dermatosis
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Schamberg disease ― 26-ročný muž s asymptomatickou pigmentáciou a teleangiektáziou na nohe.
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References
Pigmented Purpuric Dermatoses: A Complete Narrative Review 34070260 NIH
Pigmented purpuric dermatoses (PPD) je skupina kožných stavov, ktoré sa vyznačujú malými oblasťami krvácania pod kožou v dôsledku zápalu kapilár. PPD zvyčajne začína ako červené až fialové škvrny, ktoré sa neskôr menia na zlatohnedé, keď sa hemosiderín reabsorbuje.
Pigmented purpuric dermatoses (PPD) include several skin diseases characterized by multiple petechial hemorrhage as consequence of capillaritis. PPD generally present with red to purple macules that progressively evolve to golden-brown color as the hemosiderin is reabsorbed.
Schamberg Disease 32809367 NIH
Schamberg disease je najbežnejší typ pigmented purpuric dermatoses (PPDs) , čo sú chronické kožné ochorenia charakterizované malými červenými alebo fialovými škvrnami a zvýšeným sfarbením kože (hnedé, červené alebo žlté škvrny) . PPD sú rozdelené do piatich typov: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura, and eczematoid-like purpura of Doucas and Kapetanakis. Schamberg disease (SD) je tiež známy ako progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressiva, and Schamberg's purpura. Postihuje najmä mužov a zvyčajne sa objavuje na dolných končatinách, ale môže sa vyskytnúť aj na stehnách, zadku, trupe alebo rukách.
Schamberg disease represents the most common type of pigmented purpuric dermatoses (PPDs), a chronic, benign, cutaneous eruptions characterized by petechiae, purpura, and increased skin pigmentation (brown, red, or yellow patchy). The PPDs are grouped into five clinical entities: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura and, eczematoid-like purpura of Doucas and Kapetanakis. Schamber disease (SD) has also been called: progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressive and, Schamberg's purpura. It is commonly seen in males and mainly affects the tibial regions, and could involve thighs, buttocks, trunk, or upper extremities.
Characteristics and Clinical Manifestations of Pigmented Purpuric Dermatosis 26273156 NIH
Analyzovali sa informácie o 113 pacientoch s PPD, vrátane 38, ktorí pre túto štúdiu podstúpili biopsiu kože. Najčastejším klinickým typom bola Schambergova choroba (60,5 %) . Ďalšími ochoreniami popri PPD boli hypertenzia (15,8 %) , diabetes (10,5 %) a iné. Anamnéza liekov odhalila statíny (13,2 %) , betablokátory (10,5 %) a iné. Možné faktory spojené s PPD zahŕňali nedávnu infekciu horných dýchacích ciest (5,3 %) , dlhodobé státie vedúce k vysokému ortostatickému tlaku (2,6 %) a namáhavé cvičenie (2,6 %) . Liečba bola podaná 36 pacientom (94,7 %) - oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.
Information on 113 patients with PPD was analyzed, and 38 subjects with skin biopsy were included for this study. Schamberg's disease was the most frequent clinical type (60.5%). Concomitant diseases included hypertension (15.8%), diabetes (10.5%), and others. Associated medication histories included statins (13.2%), beta blockers (10.5%), and others. Possibly associated etiologic factors were recent upper respiratory infection (5.3%), high orthostatic pressure due to prolonged standing (2.6%), and strenuous exercise (2.6%). A total of 36 patients (94.7%) were treated with one or more treatment methods, including oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.
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